The Crawford W. Long Museum commemorates Dr. Long's discovery of ether's use as an anesthetic on this site March 30, 1842. The three building complex houses a medical gallery honoring Dr. Long with exhibits of personal family heirlooms as well as displays showing the development of modern anesthesia.

The museum features not only medical equipment from the 19th century, but examples of furniture, textiles and exhibits on the history of education, business and religious life in Jackson County. Visitors to the museum end their tour in the re-created Pendergrass Store, a dry-goods store opened by the Pendergrass family in 1858, which has been restocked with historically accurate merchandise.